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R&D Systems monoclonal rat anti mouse epo
In vivo neutralization of <t>EPO</t> reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg <t>monoclonal</t> anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.
Monoclonal Rat Anti Mouse Epo, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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R&D Systems monoclonal antibody targeting epo
In vivo neutralization of <t>EPO</t> reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg <t>monoclonal</t> anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.
Monoclonal Antibody Targeting Epo, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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R&D Systems human epo
In vivo neutralization of <t>EPO</t> reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg <t>monoclonal</t> anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.
Human Epo, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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R&D Systems mouse monoclonal antibody against recombinant human epo
In vivo neutralization of <t>EPO</t> reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg <t>monoclonal</t> anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.
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R&D Systems a monoclonal antibody against epo
In vivo neutralization of <t>EPO</t> reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg <t>monoclonal</t> anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.
A Monoclonal Antibody Against Epo, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


In vivo neutralization of EPO reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg monoclonal anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Article Title: Innate Immune Activation during Salmonella Infection Initiates Extramedullary Erythropoiesis and Splenomegaly

doi: 10.4049/jimmunol.1001198

Figure Lengend Snippet: In vivo neutralization of EPO reduces splenic erythroid expansion and bacterial counts. C57BL/6 mice were infected i.v. with 5 × 105 attenuated Salmonella, and 250 μg monoclonal anti-EPO or isotype control-Ig was injected 2 and 4 d later. Seven days postinfection, spleens were harvested, splenic erythroid cell populations were examined by flow cytometry, and bacterial counts determined. Bar graphs show (A) mean Ter119+/CD71+ cells in the spleen ± SD and (B) mean bacterial counts ± SD for five mice per group. The mean percentage of Ter119+/CD71+ cells in the spleen and mean bacterial counts were significantly lower in anti-EPO–treated mice, as assessed by Student t test; *p < 0.05.

Article Snippet: In vivo blockade of EPO Salmonella -infected mice were injected i.v. with 250 μg monoclonal rat anti-mouse EPO or rat IgG2a isotype control (R&D Systems) in PBS, 2 and 4 d postinfection.

Techniques: In Vivo, Neutralization, Infection, Control, Injection, Flow Cytometry